9j7a: Difference between revisions
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==local refinement of FEM1B bound with TOM20 (dimer)== | |||
<StructureSection load='9j7a' size='340' side='right'caption='[[9j7a]], [[Resolution|resolution]] 4.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9j7a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9J7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9J7A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.13Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9j7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9j7a OCA], [https://pdbe.org/9j7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9j7a RCSB], [https://www.ebi.ac.uk/pdbsum/9j7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9j7a ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FEM1B_HUMAN FEM1B_HUMAN] Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.<ref>PMID:10542291</ref> <ref>PMID:19330022</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Xu C]] | |||
[[Category: Zhao S]] | |||
Latest revision as of 08:09, 9 April 2025
local refinement of FEM1B bound with TOM20 (dimer)
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