9h1f: Difference between revisions
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==Cofilin-1 in complex with high-affinity Sybody B12== | |||
<StructureSection load='9h1f' size='340' side='right'caption='[[9h1f]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9h1f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9H1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9H1F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9h1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9h1f OCA], [https://pdbe.org/9h1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9h1f RCSB], [https://www.ebi.ac.uk/pdbsum/9h1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9h1f ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/COF1_HUMAN COF1_HUMAN] Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:15580268</ref> <ref>PMID:21834987</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Paraschiakos T]] | |||
[[Category: Pogenberg V]] | |||
[[Category: Windhorst S]] | |||
Latest revision as of 06:33, 19 March 2025
Cofilin-1 in complex with high-affinity Sybody B12
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