9k8m: Difference between revisions
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==Hypoxanthine-guanine phosphoribosyltransferase from E. coli with HEPES== | |||
<StructureSection load='9k8m' size='340' side='right'caption='[[9k8m]], [[Resolution|resolution]] 2.08Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9k8m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K8M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k8m OCA], [https://pdbe.org/9k8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k8m RCSB], [https://www.ebi.ac.uk/pdbsum/9k8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k8m ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/HPRT_ECOL6 HPRT_ECOL6] Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.[UniProtKB:P0A9M2] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | |||
[[Category: Abramchik YA]] | |||
[[Category: Esipov RS]] | |||
[[Category: Kostromina MA]] | |||
[[Category: Kuranova IP]] | |||
[[Category: Shevtsov MB]] | |||
[[Category: Timofeev VI]] | |||
[[Category: Zayats EA]] | |||
Latest revision as of 08:19, 6 November 2024
Hypoxanthine-guanine phosphoribosyltransferase from E. coli with HEPES
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