9k9t: Difference between revisions
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==MPXV DNA polymerase in complex with CDV== | |||
<StructureSection load='9k9t' size='340' side='right'caption='[[9k9t]], [[Resolution|resolution]] 2.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9k9t]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K9T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.96Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k9t OCA], [https://pdbe.org/9k9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k9t RCSB], [https://www.ebi.ac.uk/pdbsum/9k9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k9t ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/DPOL_MONPV DPOL_MONPV] Catalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral OPG148 and OPG116 proteins, thereby forming the DNA polymerase holoenzyme. Displays 3'- to 5' exonuclease activity. Might participate in viral DNA recombination. Does not perform OPG116/D4synthesis across an abasic site.[UniProtKB:P06856] | ||
[[Category: Kuai | __TOC__ | ||
[[Category: Peng | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Monkeypox virus]] | ||
[[Category: | [[Category: Ding Q]] | ||
[[Category: Wang | [[Category: Gao F]] | ||
[[Category: | [[Category: Kuai L]] | ||
[[Category: Li XM]] | |||
[[Category: Peng Q]] | |||
[[Category: Qi JX]] | |||
[[Category: Shi Y]] | |||
[[Category: Wang H]] | |||
[[Category: Wang Q]] | |||
[[Category: Xie YF]] | |||