1xp9: Difference between revisions
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New page: left|200px<br /> <applet load="1xp9" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xp9, resolution 1.80Å" /> '''HUMAN ESTROGEN RECE... |
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[[Image:1xp9.gif|left|200px]]<br /> | [[Image:1xp9.gif|left|200px]]<br /><applet load="1xp9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="1xp9" size=" | |||
caption="1xp9, resolution 1.80Å" /> | caption="1xp9, resolution 1.80Å" /> | ||
'''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 18'''<br /> | '''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 18'''<br /> | ||
==Overview== | ==Overview== | ||
A series of dihydrobenzoxathiin SERAMs with alkylated pyrrolidine side | A series of dihydrobenzoxathiin SERAMs with alkylated pyrrolidine side chains or alkylated linkers was prepared. Minor modifications in the side chain or linker resulted in significant effects on biological activity, especially in uterine tissue. | ||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
1XP9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with AIJ as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | 1XP9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=AIJ:'>AIJ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XP9 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Fitzgerald, P | [[Category: Fitzgerald, P M.D.]] | ||
[[Category: Sharma, N.]] | [[Category: Sharma, N.]] | ||
[[Category: AIJ]] | [[Category: AIJ]] | ||
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[[Category: transcription factor]] | [[Category: transcription factor]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:57:20 2008'' | ||
