1u9w: Difference between revisions

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[[Image:1u9w.gif|left|200px]]
{{Seed}}
[[Image:1u9w.png|left|200px]]


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{{STRUCTURE_1u9w|  PDB=1u9w  |  SCENE=  }}  
{{STRUCTURE_1u9w|  PDB=1u9w  |  SCENE=  }}  


'''Crystal Structure of the Cysteine Protease Human Cathepsin K in Complex with the Covalent Inhibitor NVP-ABI491'''
===Crystal Structure of the Cysteine Protease Human Cathepsin K in Complex with the Covalent Inhibitor NVP-ABI491===




==Overview==
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Starting from the high-throughput screening hit 1a, novel cathepsin K inhibitors have been developed based on a purine scaffold. High-resolution X-ray structures of several derivatives have revealed the binding mode of these unique cysteine protease inhibitors.
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{{ABSTRACT_PUBMED_15537340}}


==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Sulfhydryl proteinase]]
[[Category: Sulfhydryl proteinase]]
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