9dzo: Difference between revisions

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'''Unreleased structure'''


The entry 9dzo is ON HOLD  until Paper Publication
==Structure of ALAS bound to succinyl-CoA from S. cerevisiae==
 
<StructureSection load='9dzo' size='340' side='right'caption='[[9dzo]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
Authors: Tran, J.U., Brown, B.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9dzo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DZO FirstGlance]. <br>
Description: Structure of ALAS bound to succinyl-CoA from S. cerevisiae
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.691&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SCA:SUCCINYL-COENZYME+A'>SCA</scene></td></tr>
[[Category: Brown, B.L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dzo OCA], [https://pdbe.org/9dzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dzo RCSB], [https://www.ebi.ac.uk/pdbsum/9dzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dzo ProSAT]</span></td></tr>
[[Category: Tran, J.U]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/HEM1_YEAST HEM1_YEAST] Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.<ref>PMID:6381051</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Brown BL]]
[[Category: Tran JU]]