9k2e: Difference between revisions
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==Crystal structure of mSMPDL3B-dimer== | |||
<StructureSection load='9k2e' size='340' side='right'caption='[[9k2e]], [[Resolution|resolution]] 2.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9k2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K2E FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k2e OCA], [https://pdbe.org/9k2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k2e RCSB], [https://www.ebi.ac.uk/pdbsum/9k2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k2e ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ASM3B_MOUSE ASM3B_MOUSE] Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (PubMed:26095358).<ref>PMID:26095358</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Fan SL]] | |||
[[Category: Hou YF]] | |||
[[Category: Liu PY]] | |||
[[Category: Zhang CG]] | |||
Latest revision as of 09:13, 22 October 2025
Crystal structure of mSMPDL3B-dimer
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