1uot: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1uot.gif|left|200px]]
{{Seed}}
[[Image:1uot.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1uot|  PDB=1uot  |  SCENE=  }}  
{{STRUCTURE_1uot|  PDB=1uot  |  SCENE=  }}  


'''HUMAN CD55 DOMAINS 3 & 4'''
===HUMAN CD55 DOMAINS 3 & 4===




==Overview==
<!--  
Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection. We describe the x-ray structure of a pathogen-binding fragment of human CD55 at 1.7 A resolution containing two of the three domains required for regulation of human complement. We have used mutagenesis to map biological functions onto the molecule; decay-accelerating activity maps to a single face of the molecule, whereas bacterial and viral pathogens recognize a variety of different sites on CD55.
The line below this paragraph, {{ABSTRACT_PUBMED_12499389}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12499389 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12499389}}


==About this Structure==
==About this Structure==
Line 37: Line 41:
[[Category: Immune system protein]]
[[Category: Immune system protein]]
[[Category: Ligand for cd97]]
[[Category: Ligand for cd97]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 11:30:36 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:39:47 2008''

Revision as of 21:39, 28 July 2008

File:1uot.png

Template:STRUCTURE 1uot

HUMAN CD55 DOMAINS 3 & 4

Template:ABSTRACT PUBMED 12499389

About this Structure

1UOT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A., Williams P, Chaudhry Y, Goodfellow IG, Billington J, Powell R, Spiller OB, Evans DJ, Lea S, J Biol Chem. 2003 Mar 21;278(12):10691-6. Epub 2002 Dec 22. PMID:12499389

Page seeded by OCA on Tue Jul 29 00:39:47 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA