8x7h: Difference between revisions
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==Crystal structure of the ternary complex of GID4-PROTAC(NEP162)-BRD4(BD1).== | |||
<StructureSection load='8x7h' size='340' side='right'caption='[[8x7h]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8x7h]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X7H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=YBI:~{N}-[4-[6-[3-[4-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoyl]piperazin-1-yl]propoxy]-1~{H}-benzimidazol-2-yl]cyclohexyl]-2-(1~{H}-indol-2-ylmethylamino)ethanamide'>YBI</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x7h OCA], [https://pdbe.org/8x7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x7h RCSB], [https://www.ebi.ac.uk/pdbsum/8x7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x7h ProSAT]</span></td></tr> | ||
[[Category: Dong | </table> | ||
[[Category: Li | == Function == | ||
[https://www.uniprot.org/uniprot/GID4_HUMAN GID4_HUMAN] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Dong C]] | |||
[[Category: Li Y]] | |||
[[Category: Yan X]] | |||
Latest revision as of 21:36, 26 March 2025
Crystal structure of the ternary complex of GID4-PROTAC(NEP162)-BRD4(BD1).
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