8xna: Difference between revisions
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==Crystal structure of serine hydroxymethyltransferase 2== | |||
<StructureSection load='8xna' size='340' side='right'caption='[[8xna]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8xna]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XNA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr> | ||
[[Category: Fan | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xna OCA], [https://pdbe.org/8xna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xna RCSB], [https://www.ebi.ac.uk/pdbsum/8xna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xna ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fan S]] | |||
[[Category: Jin Y]] | |||
[[Category: Lv R]] | |||
[[Category: Tang M]] | |||
[[Category: Wang C]] | |||
[[Category: Wei X]] | |||
[[Category: Yang Z]] | |||
Latest revision as of 09:03, 2 April 2025
Crystal structure of serine hydroxymethyltransferase 2
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