9mnz: Difference between revisions
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==Cryo-EM structure of human MPC in complex with UK5099 in nanodiscs== | |||
<StructureSection load='9mnz' size='340' side='right'caption='[[9mnz]], [[Resolution|resolution]] 2.73Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9mnz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MNZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.73Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I2R:(~{E})-2-cyano-3-(1-phenylindol-3-yl)prop-2-enoic+acid'>I2R</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mnz OCA], [https://pdbe.org/9mnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mnz RCSB], [https://www.ebi.ac.uk/pdbsum/9mnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mnz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MPC2_HUMAN MPC2_HUMAN] Mediates the uptake of pyruvate into mitochondria.<ref>PMID:22628558</ref> <ref>PMID:26253029</ref> <ref>PMID:27317664</ref> <ref>PMID:29472561</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Feng L]] | |||
[[Category: He Z]] | |||
[[Category: Zhang J]] | |||
Latest revision as of 08:26, 5 March 2025
Cryo-EM structure of human MPC in complex with UK5099 in nanodiscs
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