9i0v: Difference between revisions
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==Crystal structure of DasR in complex with a synthetic DasR-binding RNA aptamer== | |||
<StructureSection load='9i0v' size='340' side='right'caption='[[9i0v]], [[Resolution|resolution]] 2.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9i0v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I0V FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i0v OCA], [https://pdbe.org/9i0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i0v RCSB], [https://www.ebi.ac.uk/pdbsum/9i0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i0v ProSAT]</span></td></tr> | ||
[[Category: Muller | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptomyces coelicolor]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Muller YA]] | |||
[[Category: Suess B]] | |||