DNA: Difference between revisions
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[[Image:DNA grooves.png|200px]] | [[Image:DNA grooves.png|200px]] | ||
This results in unequally spaced sugar-phosphate backbones and gives rise to <scene name='10/100853/Grooves/2'>two grooves</scene>: the | This results in unequally spaced sugar-phosphate backbones and gives rise to <scene name='10/100853/Grooves/2'>two grooves</scene>: the <scene name='DNA/Major_groove/2'>major groove</scene> and the <scene name='DNA/Major_groove/7'>minor groove</scene> of different width and depth. The <scene name='DNA/Major_groove/8'>oxygen atoms of the furanose rings</scene> are on the surface of the minor groove, and the major groove is on the opposite side. The floor or surface of major groove is filled with the <scene name='DNA/Major_floor/2'>atoms of the bases</scene>. The larger size of major groove allows for the binding of DNA specific proteins.<ref name="Saenger"> Saenger, Wolfram (1984). ''Principles of Nucleic Acid Structure '' (1st ed). Springer-Verlag. pp. 398. ISBN 0-12-645750-6.</ref><ref name='Watson'> Watson, James D, Nancy H. Hopkins, Jeffrey W. Roberts, Joan Argetsinger Steitz, Alan M.Weiner ''Molecular Biology of Gene'' (4th ed.). The Benjamin/Cummings Publishing Company Inc.pp. 239-249. ISBN 0-8053-9612-8</ref> | ||
<scene name='DNA/Major_groove/2'>major groove</scene> and the <scene name='DNA/Major_groove/7'>minor groove</scene> of different width and depth. The <scene name='DNA/Major_groove/8'>oxygen atoms of the furanose rings</scene> are on the surface of the minor groove, and the major groove is on the opposite side. The floor or surface of major groove is filled with the <scene name='DNA/Major_floor/2'>atoms of the bases</scene>. The larger size of major groove allows for the binding of DNA specific proteins.<ref name="Saenger"> Saenger, Wolfram (1984). ''Principles of Nucleic Acid Structure '' (1st ed). Springer-Verlag. pp. 398. ISBN 0-12-645750-6.</ref><ref name='Watson'> Watson, James D, Nancy H. Hopkins, Jeffrey W. Roberts, Joan Argetsinger Steitz, Alan M.Weiner ''Molecular Biology of Gene'' (4th ed.). The Benjamin/Cummings Publishing Company Inc.pp. 239-249. ISBN 0-8053-9612-8</ref> | |||
== Biological Functions == | == Biological Functions == | ||