9qw9: Difference between revisions

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'''Unreleased structure'''


The entry 9qw9 is ON HOLD  until Paper Publication
==Human vault protein - primed conformation==
 
<StructureSection load='9qw9' size='340' side='right'caption='[[9qw9]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
Authors: Lapenta, F., Marechal, N., Durand, A., Aupic, J., Cassetta, A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9qw9]] is a 78 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QW9 FirstGlance]. <br>
Description: Human vault protein -primed conformation
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qw9 OCA], [https://pdbe.org/9qw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qw9 RCSB], [https://www.ebi.ac.uk/pdbsum/9qw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qw9 ProSAT]</span></td></tr>
[[Category: Aupic, J]]
</table>
[[Category: Lapenta, F]]
== Function ==
[[Category: Cassetta, A]]
[https://www.uniprot.org/uniprot/MVP_HUMAN MVP_HUMAN] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.<ref>PMID:15133037</ref> <ref>PMID:16441665</ref> <ref>PMID:16418217</ref>
[[Category: Durand, A]]
== References ==
[[Category: Marechal, N]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aupic J]]
[[Category: Cassetta A]]
[[Category: Durand A]]
[[Category: Lapenta F]]
[[Category: Marechal N]]
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