9r0y: Difference between revisions

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'''Unreleased structure'''


The entry 9r0y is ON HOLD  until Paper Publication
==Crystal structure of NDM-1 with thiol compound 22b==
 
<StructureSection load='9r0y' size='340' side='right'caption='[[9r0y]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
Authors: Hinchliffe, P., Spencer, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9r0y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9R0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9R0Y FirstGlance]. <br>
Description: Crystal structure of NDM-1 with thiol compound 22b
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1JCK:~{N}-naphthalen-2-yl-2-sulfanyl-ethanamide'>A1JCK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Spencer, J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9r0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9r0y OCA], [https://pdbe.org/9r0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9r0y RCSB], [https://www.ebi.ac.uk/pdbsum/9r0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9r0y ProSAT]</span></td></tr>
[[Category: Hinchliffe, P]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Hinchliffe P]]
[[Category: Spencer J]]