9o5k: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9o5k is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of human SWELL1-PSA heterocomplex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9o5k]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O5K FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.19Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o5k OCA], [https://pdbe.org/9o5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o5k RCSB], [https://www.ebi.ac.uk/pdbsum/9o5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o5k ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/PSA_HUMAN PSA_HUMAN] Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.<ref>PMID:10978616</ref> <ref>PMID:11062501</ref> <ref>PMID:17154549</ref> <ref>PMID:17318184</ref> <ref>PMID:19917696</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Hagino T]]

[[Category: Qiu Z]]

[[Category: Twomey EC]]

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-'''Unreleased structure'''
-The entry 9o5k is ON HOLD  until Paper Publication
+==Cryo-EM structure of human SWELL1-PSA heterocomplex==
+<StructureSection load='9o5k' size='340' side='right'caption='[[9o5k]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9o5k]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O5K FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.19&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o5k OCA], [https://pdbe.org/9o5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o5k RCSB], [https://www.ebi.ac.uk/pdbsum/9o5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o5k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PSA_HUMAN PSA_HUMAN] Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.<ref>PMID:10978616</ref> <ref>PMID:11062501</ref> <ref>PMID:17154549</ref> <ref>PMID:17318184</ref> <ref>PMID:19917696</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Hagino T]]
+[[Category: Qiu Z]]
+[[Category: Twomey EC]]