9p0c: Difference between revisions
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==Crystal structure of Ca2+-bound RTX domain block V of adenylate cyclase toxin from Bordetella pertussis== | |||
<StructureSection load='9p0c' size='340' side='right'caption='[[9p0c]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9p0c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bordetella_pertussis Bordetella pertussis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9P0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9P0C FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9p0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9p0c OCA], [https://pdbe.org/9p0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9p0c RCSB], [https://www.ebi.ac.uk/pdbsum/9p0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9p0c ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Mai | [https://www.uniprot.org/uniprot/CYAA_BORPE CYAA_BORPE] This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bordetella pertussis]] | |||
[[Category: Large Structures]] | |||
[[Category: Chang MP]] | |||
[[Category: Fernandez D]] | |||
[[Category: Gudinas AP]] | |||
[[Category: Mai DJ]] | |||
Latest revision as of 11:39, 7 January 2026
Crystal structure of Ca2+-bound RTX domain block V of adenylate cyclase toxin from Bordetella pertussis
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