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| {{STRUCTURE_1w4s| PDB=1w4s | SCENE= }} | | {{STRUCTURE_1w4s| PDB=1w4s | SCENE= }} |
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| '''CRYSTAL STRUCTURE OF THE PROXIMAL BAH DOMAIN OF POLYBROMO'''
| | ===CRYSTAL STRUCTURE OF THE PROXIMAL BAH DOMAIN OF POLYBROMO=== |
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| ==Overview==
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| The BAH domain (bromo-associated homology domain) was first identified from a repeated motif found in the nuclear protein polybromo--a large (187 kDa) modular protein comprising six bromodomains, two BAH domains and an HMG box. To date, the BAH domain has no ascribed function, although it is found in a wide range of proteins that contain additional domains involved in either transcriptional regulation (e.g. SET, PHD and bromodomain) and/or DNA binding (HMG box and AT hook). The molecular function of polybromo itself also remains unclear, but it has been identified as a key component of an SWI/SNF (switching/sucrose non-fermenting)-related, ATP-dependent chromatin-remodelling complex PBAF (polybromo, BRG1-associated factors; also known as SWI/SNF-B or SWI/SNFbeta). We present in this paper the crystal structure of the proximal BAH domain from chicken polybromo (BAH1), at a resolution of 1.6 A (1 A=0.1 nm). Structure-based sequence analysis reveals several features that may be involved in mediating protein-protein interactions. | | The line below this paragraph, {{ABSTRACT_PUBMED_15839835}}, adds the Publication Abstract to the page |
| | (as it appears on PubMed at http://www.pubmed.gov), where 15839835 is the PubMed ID number. |
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| | {{ABSTRACT_PUBMED_15839835}} |
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| ==About this Structure== | | ==About this Structure== |
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| [[Category: Rsc]] | | [[Category: Rsc]] |
| [[Category: Swi/snf-b]] | | [[Category: Swi/snf-b]] |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:09:29 2008'' | | |
| | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:53:01 2008'' |
