9p3e: Difference between revisions

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'''Unreleased structure'''


The entry 9p3e is ON HOLD  until Paper Publication
==LC3B bound to BLM peptide==
 
<StructureSection load='9p3e' size='340' side='right'caption='[[9p3e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Kosmatka, J., Lim, D., Keating, A., Davis, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9p3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9P3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9P3E FirstGlance]. <br>
Description: LC3B bound to BLM peptide
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
[[Category: Keating, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9p3e OCA], [https://pdbe.org/9p3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9p3e RCSB], [https://www.ebi.ac.uk/pdbsum/9p3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9p3e ProSAT]</span></td></tr>
[[Category: Kosmatka, J]]
</table>
[[Category: Davis, J]]
== Disease ==
[[Category: Lim, D]]
[https://www.uniprot.org/uniprot/BLM_HUMAN BLM_HUMAN] Bloom syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/BLM_HUMAN BLM_HUMAN] Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).<ref>PMID:9388193</ref> <ref>PMID:12019152</ref> <ref>PMID:21325134</ref> <ref>PMID:23509288</ref> [https://www.uniprot.org/uniprot/MLP3B_HUMAN MLP3B_HUMAN] Involved in formation of autophagosomal vacuoles (autophagosomes).
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Davis J]]
[[Category: Keating A]]
[[Category: Kosmatka J]]
[[Category: Lim D]]
Retrieved from "https://proteopedia.org/9p3e"