9rbl: Difference between revisions
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==Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide MKV558== | |||
<StructureSection load='9rbl' size='340' side='right'caption='[[9rbl]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9rbl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RBL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H92:3-(cyclooctylamino)-5-ethoxy-2,6-bis(fluoranyl)-4-(3-oxidanylpropylsulfonyl)benzenesulfonamide'>A1H92</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rbl OCA], [https://pdbe.org/9rbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rbl RCSB], [https://www.ebi.ac.uk/pdbsum/9rbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rbl ProSAT]</span></td></tr> | ||
[[Category: Leitans | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CAH9_HUMAN CAH9_HUMAN] Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.<ref>PMID:18703501</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Leitans J]] | |||
[[Category: Tars K]] | |||
Latest revision as of 04:58, 27 May 2026
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide MKV558
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