9rf1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of human GPX4-U46C-R152K mutant== | |||
<StructureSection load='9rf1' size='340' side='right'caption='[[9rf1]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9rf1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RF1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rf1 OCA], [https://pdbe.org/9rf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rf1 RCSB], [https://www.ebi.ac.uk/pdbsum/9rf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rf1 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GPX4_HUMAN GPX4_HUMAN] Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mourao A]] | |||
[[Category: Popowicz G]] | |||
[[Category: Sattler M]] | |||
Latest revision as of 19:37, 4 December 2025
Structure of human GPX4-U46C-R152K mutant
| ||||||||||||
