9pe1: Difference between revisions
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==Structure of beta-1,3-glucan synthase in complex with caspofungin, Rho1 and long glucan== | |||
<StructureSection load='9pe1' size='340' side='right'caption='[[9pe1]], [[Resolution|resolution]] 3.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9pe1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PE1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.09Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>3PE</scene>, <scene name='pdbligand=A1CHR:(10R,12S)-10,12-dimethyltetradecanoic+acid'>A1CHR</scene>, <scene name='pdbligand=A1CHS:(4R,5R)-5-amino-N~5~-(2-aminoethyl)-4-hydroxy-L-ornithine'>A1CHS</scene>, <scene name='pdbligand=A1CHT:(2~{S},3~{S},4~{S})-2-azanyl-4-(4-hydroxyphenyl)-3,4-bis(oxidanyl)butanoic+acid'>A1CHT</scene>, <scene name='pdbligand=A1CHU:(2~{S},3~{R})-2,5-bis(azanyl)-3-oxidanyl-pentanoic+acid'>A1CHU</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=HY3:3-HYDROXYPROLINE'>HY3</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pe1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pe1 OCA], [https://pdbe.org/9pe1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pe1 RCSB], [https://www.ebi.ac.uk/pdbsum/9pe1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pe1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FKS1_YEAST FKS1_YEAST] Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS) complex. Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall. Involved in cell wall synthesis, maintenance and remodeling.<ref>PMID:11856368</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Lee SY]] | |||
[[Category: Ren Z]] | |||
Revision as of 06:28, 22 April 2026
Structure of beta-1,3-glucan synthase in complex with caspofungin, Rho1 and long glucan
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