9o2w: Difference between revisions

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'''Unreleased structure'''


The entry 9o2w is ON HOLD  until Paper Publication
==Crystal structure of NDM-1 complexed with compound 3==
 
<StructureSection load='9o2w' size='340' side='right'caption='[[9o2w]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
Authors: Jacobs, L.M.C., Chen, Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9o2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9O2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9O2W FirstGlance]. <br>
Description: Crystal structure of NDM-1 complexed with compound 3
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1B7Y:[(7-cyclopropyl-6-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl]phosphonic+acid'>A1B7Y</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Jacobs, L.M.C]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9o2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9o2w OCA], [https://pdbe.org/9o2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9o2w RCSB], [https://www.ebi.ac.uk/pdbsum/9o2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9o2w ProSAT]</span></td></tr>
[[Category: Chen, Y]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Chen Y]]
[[Category: Jacobs LMC]]
Retrieved from "https://proteopedia.org/9o2w"