9pmw: Difference between revisions
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The entry | ==Structure of HTTQ23-HAP40 complex bound to macrocycles HHL1, HD4 and HL2== | ||
<StructureSection load='9pmw' size='340' side='right'caption='[[9pmw]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9pmw]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PMW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pmw OCA], [https://pdbe.org/9pmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pmw RCSB], [https://www.ebi.ac.uk/pdbsum/9pmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pmw ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] Juvenile Huntington disease;Huntington disease. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] May play a role in microtubule-mediated transport or vesicle function. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Balakrishnan S]] | |||
[[Category: Deme J]] | |||
[[Category: Harding RJ]] | |||
[[Category: Lea SM]] | |||
Latest revision as of 06:23, 20 August 2025
Structure of HTTQ23-HAP40 complex bound to macrocycles HHL1, HD4 and HL2
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