9pvn: Difference between revisions

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'''Unreleased structure'''


The entry 9pvn is ON HOLD  until Paper Publication
==Human malic enzyme 3 complex with inhibitor NPD-389 at 1.82 Angstrom.==
 
<StructureSection load='9pvn' size='340' side='right'caption='[[9pvn]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
Authors: Krinkel, B.A., Yosaatmadja, Y., Squire, C.J., Loomes, K.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9pvn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PVN FirstGlance]. <br>
Description: Human malic enzyme 3 complex with inhibitor NPD-389 at 1.82 Angstrom.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AE5:2~3~,2~6~-dihydroxy-1~4~,3~4~-dimethoxy[1~1~,2~1~ 2~4~,3~1~-terphenyl]-2~2~,2~5~-dione'>A1AE5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Krinkel, B.A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pvn OCA], [https://pdbe.org/9pvn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pvn RCSB], [https://www.ebi.ac.uk/pdbsum/9pvn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pvn ProSAT]</span></td></tr>
[[Category: Loomes, K.M]]
</table>
[[Category: Squire, C.J]]
== Function ==
[[Category: Yosaatmadja, Y]]
[https://www.uniprot.org/uniprot/MAON_HUMAN MAON_HUMAN] Catalyzes the oxidative decarboxylation of (S)-malate to pyruvate using NADP(+) as a cofactor (PubMed:7818469). Can also reverse the decarboxylation reaction, but only with significantly lower efficiency (PubMed:7818469).<ref>PMID:7818469</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Krinkel BA]]
[[Category: Loomes KM]]
[[Category: Squire CJ]]
[[Category: Yosaatmadja Y]]

Latest revision as of 07:15, 5 August 2026

Human malic enzyme 3 complex with inhibitor NPD-389 at 1.82 Angstrom.

9pvn, resolution 1.82Å

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