9pwm: Difference between revisions

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'''Unreleased structure'''


The entry 9pwm is ON HOLD
==Dihydrofolate Reductase Complexed with Folate and Nicotinamide Adenine Dinucleotide Phosphate (Oxidized Form)==
 
<StructureSection load='9pwm' size='340' side='right'caption='[[9pwm]], [[Resolution|resolution]] 0.89&Aring;' scene=''>
Authors: Fried, S.D.E., Mathews, I.I., Boxer, S.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9pwm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PWM FirstGlance]. <br>
Description: Dihydrofolate Reductase Complexed with Folate and Nicotinamide Adenine Dinucleotide Phosphate (Oxidized Form)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.89&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
[[Category: Fried, S.D.E]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pwm OCA], [https://pdbe.org/9pwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pwm RCSB], [https://www.ebi.ac.uk/pdbsum/9pwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pwm ProSAT]</span></td></tr>
[[Category: Mathews, I.I]]
</table>
[[Category: Boxer, S.G]]
== Function ==
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Boxer SG]]
[[Category: Fried SDE]]
[[Category: Mathews II]]

Latest revision as of 13:20, 10 February 2026

Dihydrofolate Reductase Complexed with Folate and Nicotinamide Adenine Dinucleotide Phosphate (Oxidized Form)

9pwm, resolution 0.89Å

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