9w2n: Difference between revisions

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'''Unreleased structure'''


The entry 9w2n is ON HOLD  until 2027-07-28
==Crystal structure of the mutant LC3B in complex with p62==
 
<StructureSection load='9w2n' size='340' side='right'caption='[[9w2n]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
Authors: Mathur, S., Pal, R.K., Biswal, B.K., Thukral, L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9w2n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W2N FirstGlance]. <br>
Description: Crystal structure of the mutant LC3B in complex with p62
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Biswal, B.K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w2n OCA], [https://pdbe.org/9w2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w2n RCSB], [https://www.ebi.ac.uk/pdbsum/9w2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w2n ProSAT]</span></td></tr>
[[Category: Thukral, L]]
</table>
[[Category: Pal, R.K]]
== Function ==
[[Category: Mathur, S]]
[https://www.uniprot.org/uniprot/MLP3B_MOUSE MLP3B_MOUSE] Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.[UniProtKB:Q9GZQ8]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Biswal BK]]
[[Category: Mathur S]]
[[Category: Pal RK]]
[[Category: Thukral L]]
Retrieved from "https://proteopedia.org/9w2n"