9krp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9krp is ~~ON HOLD until Paper Publication~~

==Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9krp]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KRP OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9KRP FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9krp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9krp OCA], [https://pdbe.org/9krp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9krp RCSB], [https://www.ebi.ac.uk/pdbsum/9krp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9krp ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/RSSA_HUMAN RSSA_HUMAN] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.<ref>PMID:6300843</ref> <ref>PMID:16263087</ref> <ref>PMID:15516338</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Imami K]]

[[Category: Imataka H]]

[[Category: Ito T]]

[[Category: Iwasaki S]]

[[Category: Iwasaki W]]

[[Category: Kashiwagi K]]

[[Category: Machida K]]

[[Category: Matsumoto A]]

[[Category: Nishimoto M]]

[[Category: Sakamoto A]]

[[Category: Shichino Y]]

[[Category: Takahashi M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9krp is ON HOLD  until Paper Publication
+==Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3==
+<StructureSection load='9krp' size='340' side='right'caption='[[9krp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9krp]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KRP FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9krp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9krp OCA], [https://pdbe.org/9krp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9krp RCSB], [https://www.ebi.ac.uk/pdbsum/9krp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9krp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RSSA_HUMAN RSSA_HUMAN] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.<ref>PMID:6300843</ref> <ref>PMID:16263087</ref> <ref>PMID:15516338</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Imami K]]
+[[Category: Imataka H]]
+[[Category: Ito T]]
+[[Category: Iwasaki S]]
+[[Category: Iwasaki W]]
+[[Category: Kashiwagi K]]
+[[Category: Machida K]]
+[[Category: Matsumoto A]]
+[[Category: Nishimoto M]]
+[[Category: Sakamoto A]]
+[[Category: Shichino Y]]
+[[Category: Takahashi M]]