9sef: Difference between revisions
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==mechanosensitive channel MscS from Francisella tularensis in nanodiscs== | |||
<StructureSection load='9sef' size='340' side='right'caption='[[9sef]], [[Resolution|resolution]] 3.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9sef]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis Francisella tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SEF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9sef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9sef OCA], [https://pdbe.org/9sef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9sef RCSB], [https://www.ebi.ac.uk/pdbsum/9sef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9sef ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A0B3VCY4_FRATU A0A0B3VCY4_FRATU] Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.[RuleBase:RU369025] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Francisella tularensis]] | |||
[[Category: Large Structures]] | |||
[[Category: Bottcher B]] | |||
[[Category: Flegler VJ]] | |||
[[Category: Hemmelmann N]] | |||
[[Category: Hove TT]] | |||
[[Category: Rasmussen A]] | |||
[[Category: Rasmussen T]] | |||