9yic: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9yic is ~~ON HOLD~~

==Crystal structure of human IL-17A in complex with Compound 1==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9yic]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YIC OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9YIC FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CXF:(3S)-N-[(3-{[(1S)-2-anilino-1-cyclohexyl-2-oxoethyl]carbamoyl}phenyl)methyl]-2,2-dimethylthiomorpholine-3-carboxamide'>A1CXF</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9yic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yic OCA], [https://pdbe.org/9yic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yic RCSB], [https://www.ebi.ac.uk/pdbsum/9yic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yic ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Armstrong AA]]

[[Category: Luo J]]

[[Category: Milligan CM]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9yic is ON HOLD
+==Crystal structure of human IL-17A in complex with Compound 1==
+<StructureSection load='9yic' size='340' side='right'caption='[[9yic]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9yic]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YIC FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CXF:(3S)-N-[(3-{[(1S)-2-anilino-1-cyclohexyl-2-oxoethyl]carbamoyl}phenyl)methyl]-2,2-dimethylthiomorpholine-3-carboxamide'>A1CXF</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yic OCA], [https://pdbe.org/9yic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yic RCSB], [https://www.ebi.ac.uk/pdbsum/9yic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yic ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Armstrong AA]]
+[[Category: Luo J]]
+[[Category: Milligan CM]]