9y0m: Difference between revisions

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'''Unreleased structure'''


The entry 9y0m is ON HOLD  until Paper Publication
==Crystal structure of Escherichia coli DsbA P151T mutant==
 
<StructureSection load='9y0m' size='340' side='right'caption='[[9y0m]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
Authors: Cunliffe, T.R., Heras, B., Paxman, J.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9y0m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Y0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Y0M FirstGlance]. <br>
Description: Crystal structure of Escherichia coli DsbA P151T mutant
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.88&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[Category: Heras, B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9y0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9y0m OCA], [https://pdbe.org/9y0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9y0m RCSB], [https://www.ebi.ac.uk/pdbsum/9y0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9y0m ProSAT]</span></td></tr>
[[Category: Paxman, J.J]]
</table>
[[Category: Cunliffe, T.R]]
== Function ==
[https://www.uniprot.org/uniprot/DSBA_ECOLI DSBA_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.<ref>PMID:1429594</ref> <ref>PMID:22267510</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Cunliffe TR]]
[[Category: Heras B]]
[[Category: Paxman JJ]]
Retrieved from "https://proteopedia.org/9y0m"