9t29: Difference between revisions
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==Jumonji domain-containing protein 2D with crystallization epitope mutation Q41R== | |||
<StructureSection load='9t29' size='340' side='right'caption='[[9t29]], [[Resolution|resolution]] 2.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9t29]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T29 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.013Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t29 OCA], [https://pdbe.org/9t29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t29 RCSB], [https://www.ebi.ac.uk/pdbsum/9t29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t29 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/KDM4D_HUMAN KDM4D_HUMAN] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.<ref>PMID:16603238</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Mackinnon | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Burgess-Brown N]] | ||
[[Category: | [[Category: Damerell D]] | ||
[[Category: | [[Category: Edwards A]] | ||
[[Category: | [[Category: Fairhead M]] | ||
[[Category: Koekemoer L]] | |||
[[Category: Krojer T]] | |||
[[Category: MacLean EM]] | |||
[[Category: Mackinnon SR]] | |||
[[Category: Marsden B]] | |||
[[Category: Pinkas D]] | |||
[[Category: Strain-Damerell C]] | |||
[[Category: Ye M]] | |||
[[Category: Yue W]] | |||
[[Category: Von Delft F]] | |||