9yfw: Difference between revisions
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The entry | ==VPS13A central bridge domain== | ||
<StructureSection load='9yfw' size='340' side='right'caption='[[9yfw]], [[Resolution|resolution]] 3.21Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9yfw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YFW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yfw OCA], [https://pdbe.org/9yfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yfw RCSB], [https://www.ebi.ac.uk/pdbsum/9yfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yfw ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/VP13A_HUMAN VP13A_HUMAN] Choreoacanthocytosis. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VP13A_HUMAN VP13A_HUMAN] Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids (PubMed:34830155). Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria (PubMed:30741634). Negatively regulates lipid droplet size and motility (PubMed:30741634). Required for efficient lysosomal protein degradation (PubMed:30709847).[UniProtKB:Q07878]<ref>PMID:30709847</ref> <ref>PMID:30741634</ref> <ref>PMID:34830155</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hu B]] | |||
[[Category: Reinisch KM]] | |||
