9x5g: Difference between revisions
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==Cryo-EM structure of quinary complex GA3-MtGID1b-MtDELLA1-SLY1-ASK1== | |||
<StructureSection load='9x5g' size='340' side='right'caption='[[9x5g]], [[Resolution|resolution]] 3.24Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9x5g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Medicago_truncatula Medicago truncatula]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9X5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9X5G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.24Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA3:GIBBERELLIN+A3'>GA3</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9x5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9x5g OCA], [https://pdbe.org/9x5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9x5g RCSB], [https://www.ebi.ac.uk/pdbsum/9x5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9x5g ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DELA1_MEDTR DELA1_MEDTR] Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway (By similarity). Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes (By similarity). Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway (By similarity). Together with DELLA2, required to enable arbuscule development during arbuscular mycorrhizal (AM) symbiosis with AM fungi (e.g. Glomus versiforme) via the regulation of RAM1 which, in turn, regulates various AM genes (e.g. NSP1, NSP2, PT4, LEC5, RAM2, EXO70I, STR and RAD1) (PubMed:24297892, PubMed:26511916).[UniProtKB:Q7G7J6]<ref>PMID:24297892</ref> <ref>PMID:26511916</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Medicago truncatula]] | |||
[[Category: Wan LH]] | |||