9sxi: Difference between revisions
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==HUMAN CD38 ECTODOMAIN BOUND TO CVN14-ADPR ADDUCT== | |||
<StructureSection load='9sxi' size='340' side='right'caption='[[9sxi]], [[Resolution|resolution]] 1.74Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9sxi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SXI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1JSF:[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{R})-5-[3-[4-methyl-6-[[4-[2,2,2-tris(fluoranyl)ethylamino]cyclohexyl]carbamoyl]pyrimidin-2-yl]imidazol-3-ium-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl+hydrogen+phosphate'>A1JSF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9sxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9sxi OCA], [https://pdbe.org/9sxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9sxi RCSB], [https://www.ebi.ac.uk/pdbsum/9sxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9sxi ProSAT]</span></td></tr> | ||
[[Category: Rangel | </table> | ||
[[Category: Zebisch | == Function == | ||
[https://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Rangel V]] | |||
[[Category: Stott A]] | |||
[[Category: Zebisch M]] | |||
Latest revision as of 07:28, 11 February 2026
HUMAN CD38 ECTODOMAIN BOUND TO CVN14-ADPR ADDUCT
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