Sandbox: Difference between revisions
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===Mechanism of OAT1 inhibition by probenecid=== | ===Mechanism of OAT1 inhibition by probenecid=== | ||
The cryo-EM structure of hOAT1 bound to the classic inhibitor probenecid reveals a dual-mechanism of action that goes beyond simple competition, effectively arresting the transporter in a restricted state. | The cryo-EM structure of <scene name='85/857155/Prob/1'>hOAT1 bound to the classic inhibitor probenecid</scene> reveals a dual-mechanism of action that goes beyond simple competition, effectively arresting the transporter in a restricted state. | ||
'''1. Binding Mode and Direct Competition''' | '''1. Binding Mode and Direct Competition''' | ||
