9z3t: Difference between revisions
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==Crystal structure of the activin B:follistatin 288 complex== | |||
<StructureSection load='9z3t' size='340' side='right'caption='[[9z3t]], [[Resolution|resolution]] 2.72Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9z3t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Z3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Z3T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9z3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9z3t OCA], [https://pdbe.org/9z3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9z3t RCSB], [https://www.ebi.ac.uk/pdbsum/9z3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9z3t ProSAT]</span></td></tr> | ||
[[Category: Howard | </table> | ||
[[Category: | == Function == | ||
[[Category: Walker | [https://www.uniprot.org/uniprot/INHBB_HUMAN INHBB_HUMAN] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Goebel EJ]] | |||
[[Category: Howard JA]] | |||
[[Category: Thompson TB]] | |||
[[Category: Walker RG]] | |||