9z4o: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
The entry | ==Cryo-EM structure of human Wntless in its apo state== | ||
<StructureSection load='9z4o' size='340' side='right'caption='[[9z4o]], [[Resolution|resolution]] 2.63Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9z4o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Z4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Z4O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.63Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9z4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9z4o OCA], [https://pdbe.org/9z4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9z4o RCSB], [https://www.ebi.ac.uk/pdbsum/9z4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9z4o ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/WLS_HUMAN WLS_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/WLS_HUMAN WLS_HUMAN] Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins (PubMed:34587386). Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).<ref>PMID:16678095</ref> <ref>PMID:16678096</ref> <ref>PMID:34587386</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ge Y]] | |||
[[Category: Huang P]] | |||
[[Category: Jiang J]] | |||
[[Category: Salic A]] | |||
[[Category: Wang Z]] | |||
[[Category: Wu H]] | |||
[[Category: Yadav GP]] | |||
[[Category: De Almeida Magalhaes T]] | |||
Latest revision as of 15:23, 10 June 2026
Cryo-EM structure of human Wntless in its apo state
| ||||||||||||
