9zb2: Difference between revisions
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==Crystal structure of human MGAT1 in complex with TNG-9333 and UDP.== | |||
<StructureSection load='9zb2' size='340' side='right'caption='[[9zb2]], [[Resolution|resolution]] 2.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9zb2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZB2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1C1W:~{N}-[2-(aminomethyl)-6-[ethanoyl(methyl)amino]pyridin-4-yl]-2-cyclobutyloxy-quinoline-4-carboxamide'>A1C1W</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zb2 OCA], [https://pdbe.org/9zb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zb2 RCSB], [https://www.ebi.ac.uk/pdbsum/9zb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zb2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MGAT1_HUMAN MGAT1_HUMAN] Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.<ref>PMID:1702225</ref> <ref>PMID:36280670</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Handing KB]] | |||
[[Category: Whittington DA]] | |||
Latest revision as of 16:37, 25 September 2026
Crystal structure of human MGAT1 in complex with TNG-9333 and UDP.
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