9tpg: Difference between revisions

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'''Unreleased structure'''


The entry 9tpg is ON HOLD
==Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 1==
 
<StructureSection load='9tpg' size='340' side='right'caption='[[9tpg]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9tpg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9TPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9TPG FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H2Z:(1~{E})-1-[3-[(2~{R})-1-phenylpropan-2-yl]-2~{H}-1,2,3-oxadiazol-3-ium-5-ylidene]-3-[3-(trifluoromethyl)phenyl]urea'>A1H2Z</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9tpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9tpg OCA], [https://pdbe.org/9tpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9tpg RCSB], [https://www.ebi.ac.uk/pdbsum/9tpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9tpg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A140DLX4_ZIKV A0A140DLX4_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Zika virus]]
[[Category: Ontoria JM]]
[[Category: Torrente E]]
Retrieved from "https://proteopedia.org/9tpg"