9zoq: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9zoq is ~~ON HOLD~~

==OXA-23-JDB/PQ-1-219, 5 min soak==

~~Authors~~: ~~Smith~~, C.A., ~~Maggiolo, A~~.M., ~~Vakulenko~~, S.B., ~~Toth~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[9zoq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZOQ OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9ZOQ FirstGlance].

~~Description~~: ~~OXA~~-23-~~JDB/PQ~~-1-~~219~~, ~~5 min soak~~

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Toth, M~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9zoq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zoq OCA], [https://pdbe.org/9zoq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zoq RCSB], [https://www.ebi.ac.uk/pdbsum/9zoq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zoq ProSAT]</td></tr>

[[Category: Smith~~, C.A~~]]

</table>

[[Category: ~~Vakulenko, S.B~~]]

== Function ==

[[Category: ~~Maggiolo, A.M~~]]

[https://www.uniprot.org/uniprot/BLO23_ACIBA BLO23_ACIBA] Class D beta-lactamase which confers resistance to the beta-lactam antibiotics, including ampicillin, and carbapenems such as imipenem and meropenem (PubMed:18725452, PubMed:20194701, PubMed:24012371, PubMed:30530607, PubMed:35420470). Acts via hydrolysis of the beta-lactam ring (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities, but lacks ceftazidime-hydrolyzing activity (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470).<ref>PMID:18725452</ref> <ref>PMID:20194701</ref> <ref>PMID:23877677</ref> <ref>PMID:24012371</ref> <ref>PMID:30530607</ref> <ref>PMID:35420470</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Acinetobacter baumannii]]

[[Category: Large Structures]]

[[Category: Maggiolo AM]]

[[Category: Smith CA]]

[[Category: Toth M]]

[[Category: Vakulenko SB]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9zoq is ON HOLD
+==OXA-23-JDB/PQ-1-219, 5 min soak==
+<StructureSection load='9zoq' size='340' side='right'caption='[[9zoq]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-Authors: Smith, C.A., Maggiolo, A.M., Vakulenko, S.B., Toth, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9zoq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZOQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZOQ FirstGlance]. <br>
-Description: OXA-23-JDB/PQ-1-219, 5 min soak
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Toth, M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zoq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zoq OCA], [https://pdbe.org/9zoq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zoq RCSB], [https://www.ebi.ac.uk/pdbsum/9zoq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zoq ProSAT]</span></td></tr>
-[[Category: Smith, C.A]]
+</table>
-[[Category: Vakulenko, S.B]]
+== Function ==
-[[Category: Maggiolo, A.M]]
+[https://www.uniprot.org/uniprot/BLO23_ACIBA BLO23_ACIBA] Class D beta-lactamase which confers resistance to the beta-lactam antibiotics, including ampicillin, and carbapenems such as imipenem and meropenem (PubMed:18725452, PubMed:20194701, PubMed:24012371, PubMed:30530607, PubMed:35420470). Acts via hydrolysis of the beta-lactam ring (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities, but lacks ceftazidime-hydrolyzing activity (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470).<ref>PMID:18725452</ref> <ref>PMID:20194701</ref> <ref>PMID:23877677</ref> <ref>PMID:24012371</ref> <ref>PMID:30530607</ref> <ref>PMID:35420470</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Acinetobacter baumannii]]
+[[Category: Large Structures]]
+[[Category: Maggiolo AM]]
+[[Category: Smith CA]]
+[[Category: Toth M]]
+[[Category: Vakulenko SB]]