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'''Unreleased structure'''


The entry 22tn is ON HOLD
==Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor==
 
<StructureSection load='22tn' size='340' side='right'caption='[[22tn]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
Authors: Li, S., Zhou, L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[22tn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=22TN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=22TN FirstGlance]. <br>
Description: Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1E4Q:~{N}-[5-(4-chlorophenyl)-2-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]-4-phenyl-benzenesulfonamide'>A1E4Q</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
[[Category: Li, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=22tn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=22tn OCA], [https://pdbe.org/22tn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=22tn RCSB], [https://www.ebi.ac.uk/pdbsum/22tn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=22tn ProSAT]</span></td></tr>
[[Category: Zhou, L]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Li S]]
[[Category: Zhou L]]
Retrieved from "https://proteopedia.org/22tn"