9u0o: Difference between revisions
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==Priestia megaterium isoleucyl-tRNA synthetase 2 in complex with Escherichia coli tRNA-Ile-GAU and ATP== | |||
<StructureSection load='9u0o' size='340' side='right'caption='[[9u0o]], [[Resolution|resolution]] 5.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9u0o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Priestia_megaterium_NBRC_15308_=_ATCC_14581 Priestia megaterium NBRC 15308 = ATCC 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U0O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u0o OCA], [https://pdbe.org/9u0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u0o RCSB], [https://www.ebi.ac.uk/pdbsum/9u0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u0o ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A0B6AVD3_PRIM2 A0A0B6AVD3_PRIM2] Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).[ARBA:ARBA00025217][HAMAP-Rule:MF_02003] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Priestia megaterium NBRC 15308 = ATCC 14581]] | |||
[[Category: Ban N]] | |||
[[Category: Brkic A]] | |||
[[Category: Gruic-Sovulj I]] | |||
[[Category: Lecona Butelli A]] | |||
[[Category: Leibundgut M]] | |||
[[Category: Longo LM]] | |||
[[Category: Modrusan P]] | |||
[[Category: Zivkovic I]] | |||
Latest revision as of 08:39, 16 September 2026
Priestia megaterium isoleucyl-tRNA synthetase 2 in complex with Escherichia coli tRNA-Ile-GAU and ATP
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