9y77: Difference between revisions
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==Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex in complex with UMN141== | |||
<StructureSection load='9y77' size='340' side='right'caption='[[9y77]], [[Resolution|resolution]] 2.58Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9y77]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Y77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Y77 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.58Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CSZ:(9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1-(2-methylpropyl)-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2,3 7,8]naphtho[1,2-d]imidazole-2,4-piperidin]-16-yl+[(8R)-5,6-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]carbamate'>A1CSZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9y77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9y77 OCA], [https://pdbe.org/9y77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9y77 RCSB], [https://www.ebi.ac.uk/pdbsum/9y77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9y77 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOA_MYCTU RPOA_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059]<ref>PMID:22570422</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Ebright RH]] | |||
[[Category: You LL]] | |||
Latest revision as of 09:46, 30 September 2026
Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex in complex with UMN141
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