9jki: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~9jki is ON HOLD~~

==membrane protein SLC6A3 with Bpp==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9jki]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JKI OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9JKI FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.69Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1XR:(2~{S})-2-(~{tert}-butylamino)-1-(3-chlorophenyl)propan-1-one'>1XR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9jki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jki OCA], [https://pdbe.org/9jki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jki RCSB], [https://www.ebi.ac.uk/pdbsum/9jki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jki ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/SC6A3_HUMAN SC6A3_HUMAN] Infantile dystonia-parkinsonism. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/SC6A3_HUMAN SC6A3_HUMAN] Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:8302271). Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity).[UniProtKB:P23977][UniProtKB:Q61327]<ref>PMID:1406597</ref> <ref>PMID:15505207</ref> <ref>PMID:8302271</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Zhang SS]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9jki is ON HOLD
+==membrane protein SLC6A3 with Bpp==
+<StructureSection load='9jki' size='340' side='right'caption='[[9jki]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9jki]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JKI FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.69&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1XR:(2~{S})-2-(~{tert}-butylamino)-1-(3-chlorophenyl)propan-1-one'>1XR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jki OCA], [https://pdbe.org/9jki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jki RCSB], [https://www.ebi.ac.uk/pdbsum/9jki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jki ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/SC6A3_HUMAN SC6A3_HUMAN] Infantile dystonia-parkinsonism. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/SC6A3_HUMAN SC6A3_HUMAN] Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:8302271). Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity).[UniProtKB:P23977][UniProtKB:Q61327]<ref>PMID:1406597</ref> <ref>PMID:15505207</ref> <ref>PMID:8302271</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Zhang SS]]