Sigma factor 3D structures: Difference between revisions

**[[1ku2]] – TaSF-A region 1.2-3.1 – ''Thermus aquaticus''<br />

**[[1ku3]] – TaSF-A region 4 (mutant)<br />

**[[3les]] – TaSF-A residues 93-271<br />

**[[1sig]] – EcSF-70 – ''Escherichia coli''<br />

**[[2mao]] – EcSF-E region 2 - NMR<br />

**[[6fi7]] – EcSF-38 - NMR<br />

**[[1tty]] – TmSF-70 region 4 – ''Thermotoga maritima''<br />

**[[2k6x]] – TmSF-70 region 1.1 (mutant) - NMR<br />

**[[2ahq]] – AaSF-54 C terminal – ''Aquifex aeolicus'' - NMR<br />

**[[2k9l]], [[2k9m]] – AaSF-54 core domain - NMR<br />

**[[3mzy]] – SFH – ''Fusobacterium nucleatum''<br />

**[[1h3l]] – ScSF N terminal – ''Streptomyces coelicolor''<br />

**[[5fgm]] – ScSF-R region 4<br />

**[[7qh5]] – SF-G1 – ''Streptomyces tsukubensis''<br />

**[[5mww]] – BsSF-A region 1.1 - ''Bacillus subtilis'' - NMR <br />

**[[8b3z]] – BsSF-E N terminal <br />

**[[5xe7]] – MtSF-J – ''Mycobacterium tuberculosis''<br />

**[[3ugo]], [[3ugp]] - TaSF-A region 2 + DNA<br />

**[[1ku7]] – TaSF-A region 4 (mutant) + DNA <br />

**[[4ki2]] - TaSF-A region 2-3 + DNA<br />

**[[2h27]] – EcSF-E region 4 + DNA<br />

**[[2map]] – EcSF-E region 2 + DNA - NMR<br />

**[[2o8k]], [[2o9l]] – AaSF-54 C terminal + DNA - NMR<br />

**[[5ui5]] – AaSF-54 residues 61-398 + DNA <br />

**[[6jhe]] – BsSF-W region 4 + DNA <br />

**[[1tlh]] – EcSF-70 region 4 + anti-σ factor<br />

**[[1rp3]], [[1sc5]] – AaSF-28 + anti-σ factor FLGM <br />

**[[6ivu]] – CtSF-1 + anti-σ factor – ''Clostridium thermocellum''<br />

**[[5wur]] – BsSF-W + anti-σ factor <br />

**[[5uxx]] – SF + anti-σ factor – ''Bartonella quintana''<br />

**[[4nqw]] – MtSF-K region 4 + anti-σ factor<br />

**[[3lev]] – TaSF-A residues 93-271 + antibody<br />

**[[1l9u]] – TaSF-A region 1.1-4 + RNAP subunits α,β,β’,ω<br />

**[[1or7]] – EcSF-E + σ-E factor negative regulatory protein <br />

**[[4lup]] – EcSF-E residues 3-92 + EcSF region 2 <br />

**[[2p7v]] – EcSF-70 region 4 + regulator of σ D<br />

**[[4yg2]], [[5uag]], [[5uaj]], [[5uaq]] – EcSF-70 + RNAP subunits α,β,β’,ω  <br />

**[[5ui8]] – EcSF-45 + RNAP subunits α,β,β’,ω  <br />

**[[6byu]] – EcSF-70 + RNAP subunits α,β,β’,ω + ppApp <br />

**[[4mey]], [[4ljz]], [[4lk1]], [[6cux]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />

**[[6c9y]], [[6ca0]] – EcSF-70 + RNAP subunits α,β,β’,ω - Cryo EM<br />

**[[5nwt]] – EcSF-54 + RNAP subunits α,β,β’,ω <br />

**[[5w1s]] – EcSF-70 + RNAP subunits α,β,β’ + TraR<br />

**[[5vsw]] – EcSF-70 + RNAP subunits α,β,β’ + DnaK suppressor protein<br />

**[[5w1t]] – EcSF-70 + RNAP subunits α,β,β’ + RpoZ + DnaK suppressor protein<br />

**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />

**[[3hug]] – MtSF-L + membrane protein <br />

**[[4x8k]] – MtSF-A region 2 + RBPA<br />

**[[6onu]], [[6ono]] – MtSF-A region 4 + WHIB1<br />

**[[5zx3]] – MtSF-H + RNAP subunits α,β,β’,ω <br />

**[[6fbv]] – MtSF-A + RNAP subunits α,β,β’,ω - Cryo EM<br />

**[[7pp4]], [[7q4u]], [[7q59]], [[7zf2]] – MtSF-B + RNAP subunits α,β,β’,ω - Cryo EM<br />

**[[6c05]], [[6c06]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA - Cryo EM<br />

**[[3wod]], [[2a6e]], [[2cw0]], [[5tmf]] – TtSF-A + RNAP subunits α,β,β’,ω - ''Thermus thermophilus'' <br />

**[[2be5]] – TtSF-70 + RNAP subunits α,β,β’,ω + inhibitor<br />

**[[6pfj]], [[6pfv]] – ScSF (mutant) + AMFC protein<br />

**[[5tmc]] – TtSF-A + RNAP subunits α,β,β’,ω + protein + G4P<br />

**[[5xj0]] – TtSF-A + RNAP subunits α,β,β’,ω + GP39 + GP76<br />

**[[5x22]] – TtSF-A + RNAP subunits α,β,β’,ω + GpA + CMPcPP<br />

**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF7-0 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />

**[[4cxf]] – SF CNRH + CNRY – ''Cupriavidus metallidurans''<br />

**[[4g6d]], [[4g8x]], [[4g94]] – SF-70 region 4 + Orf067 – ''Staphylococcus aureus''<br />

**[[5yix]] – CcSF-70 + GcrA - ''Caulobacter crescentus''<br />

**[[6in7]] – PaSF-H + ALGU – ''Pseudomonas aeruginosa''<br />

**[[6eyd]] – MsSF-A + RNAP subunits α,β,β’,ω - ''Mycobacterium smegmatis'' – Cryo EM <br />

**[[6dxo]] – SvSF-A + BLDN – ''Streptomyces venezuelae''<br />

**[[7vf9]] – PaSF-38 + RNAP subunits α,β,β’,ω - Cryo EM<br />

**[[6p1k]], [[7khb]] – EcSF-70 + EcRNAP subunits α,β,β’,ω - Cryo EM<br />

**[[6vjs]] – EcSF-70 + EcRNAP subunits α,β,β’,ω <br />

**[[3iyd]] – EcSF-70 in transcription initiation complex + catabolite gene activator<br />

**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />

**[[7khe]], [[7khi]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P – Cryo EM<br />

**[[7khc]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + POP – Cryo EM<br />

**[[4yln]], [[4ylo]], [[4ylp]], [[6n62]], [[6utv]], [[6utw]], [[6utx]] [[6uty]], [[6utz]], [[6uu0]], [[6uu1]], [[6uuc]] [[6uu3]], [[6uu4]], [[6uu5]], [[6uu6]], [[6uu7]], [[6uu8]], [[6uu2]], [[6uua]], [[6uuc]] – EcSF-70 in transcription initiation complex<br />

**[[6b6h]], [[6xl5]], [[6xl9]], [[6xlj]], [[6xll]], [[7vwy]], [[8igr]], [[8igs]] – EcSF-70 in transcription activation complex - Cryo EM<br />

**[[5nss]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM<br />

**[[5nsr]], [[6gh6]], [[6gh5]], [[6gfw]], [[7szk]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />

**[[7bef]], [[7beg]], [[7chw]], [[7mkd]], [[7mke]], [[7mki]], [[7mkj]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />

**[[6n61]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA<br />

**[[6n60]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA<br />

**[[6p18]] – EcSF-70 in transcription antitermination complex + protein Q<br />

**[[6jnx]], [[7ubm]] – EcSF-70 in transcription antitermination complex + protein Q – Cryo EM<br />

**[[7ubn]] – EcSF-70 in transcription antitermination complex + NusA – Cryo EM<br />

**[[6jbq]] – EcSF-E in transcription initiation complex – Cryo EM<br />

**[[5vt0]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM<br />

**[[6k4y]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM<br />

**[[6ldi]], [[6xh7]], [[6xh8]], [[7c17]] – EcSF-70 in transcription activation complex + CueR – Cryo EM<br />

**[[6pb4]], [[6pb5]], [[6pb6]] – EcSF-70 in transcription activation complex + Crp – Cryo EM<br />

**[[7vwz]] – EcSF-70 in transcription activation complex + right origin-binding protein – Cryo EM<br />

**[[7w5w]], [[7w5x]], [[7w5y]] – EcSF-70 in transcription activation complex + SoxS – Cryo EM<br />

**[[8jo2]] – EcSF-70 in transcription activation complex + BasR – Cryo EM<br />

**[[6n57]], [[6n58]] – EcSF-70 in transcription initiation complex + Tsar – Cryo EM<br />

**[[6psq]], [[6psr]], [[6pss]], [[6pst]], [[6psu]], [[6psv]], [[6psw]] – EcSF-70 in transcription initiation complex + Trar – Cryo EM<br />

**[[6n4c]], [[6oul]] – EcSF-70 in transcription initiation complex – Cryo EM<br />

**[[7khe]] – EcSF-70 in transcription initiation complex + GTP – Cryo EM<br />

**[[7chw]], [[7khb]] – EcSF-70 in transcription open promoter complex – Cryo EM<br />

**[[6wmu]], [[7c97]], [[7dy6]] – EcSF-70 in transcription open promoter complex + SspA – Cryo EM<br />

**[[7khi]] – EcSF-70 in transcription open promoter complex + DKSA + G4P – Cryo EM<br />

**[[7khc]] – EcSF-70 in transcription closed promoter complex – Cryo EM<br />

**[[6xlm]], [[7n4e]], [[7xui]] – EcSF-70 in elongation complex – Cryo EM<br />

**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]], [[6p71]], [[6p70]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[7mli]], [[7mlj]]  – TtSF-A in reiterative transcription complex <br />

**[[7rdq]] – TtSF-A in reiterative transcription complex – Cryo EM<br />

**[[5vo8]] – TtSF-A in reiterative transcription complex  + GTP<br />

**[[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]], [[6lts]], [[5e17]], [[5e18]] – TtSF-A in initial<br>transcription complex <br />

**[[6wox]], [[6woy]] – TtSF-A in initial transcription complex + CPT<br />

**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />

**[[5voi]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA <br />

**[[7eh2]], [[7mlb]] – TtSF-A in transcription initiation complex <br />

**[[5d4c]] – TtSF-A in transcription initiation complex + CTP + ATP<br />

**[[5d4d]] – TtSF-A in transcription initiation complex + CTP + NAD<br />

**[[5d4e]] – TtSF-A in transcription initiation complex + CTP + dephosphate-CoA<br />

**[[5x22]], [[7eh0]], [[7eh1]] – TtSF-A in transcription initiation complex  + CMPPP<br />

**[[5i2d]] – TtSF-A in transcription activation complex  + transcriptional regulator <br />

**[[7f75]] – BsSF-A in transcription activation complex  + transcriptional regulator – Cryo EM<br />

**[[7ckq]] – BsSF-A in transcription activation complex  + multidrug regulator + YKZG – Cryo EM<br />

**[[3n97]] – TaSF-A region 4 + RNAP subunits α + DNA<br />

**[[4xln]], [[4xlp]], [[4xlq]], [[5tjg]] – TaSF-A in transcription initiation complex<br />

**[[1l9z]] – TaSF-A + RNAP subunits α,β,β’,ω + DNA – Cryo EM  <br />

**[[4xlr]], [[4xls]] – TaSF-A in transcription initiation complex + CarD-like transcriptional regulator<br />

**[[1rio]] - TaSF-A region 4 + repression protein CI + DNA<br />

**[[5uha]], [[5uh5]], [[5uh8]], [[5uh9]], [[7u22]] – MtSF-A in transcription initiation complex<br />

**[[6dcf]] – MtSF-A in transcription initiation complex + RbpA<br />

**[[8hih]] – MtSF-A in transcription initiation complex + transctriptional regulatory protein – Cryo EM<br />

**[[6c04]], [[7kin]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM<br />

**[[7kif]], [[7kim]] – MtSF-A + RNAP subunits α,β,β’,ω + WhiB7 + DNA - Cryo EM<br />

**[[5uhe]], [[5uhf]] – MtSF-A in transcription initiation complex + inhibitor<br />

**[[6jcy]], [[6jcx]], [[5zx2]] – MtSF-H in transcription initiation complex<br />

**[[6kon]], [[6koo]], [[6kop]], [[6koq]] – MtSF-H in transcription initiation complex <br />

**[[6dve]], [[6dvd]], [[7rwi]] – MtSF-L in transcription initiation complex<br />

**[[6dvc]], [[6dvb]], [[6dv9]], [[6tye]], [[6tyf]], [[6tyg]] – MtSF-L in transcription initiation complex <br />

**[[5tw1]], [[6cce]] – MsSF-A in transcription initiation complex + peptide - ''Mycobacterium smegmatis''<br />

**[[5vi5]], [[5vi8]], [[6vvv]] – MsSF-A in transcription initiation complex<br />

**[[7p5x]] – MsSF-A in transcription initiation complex + PafBC – Cryo EM<br />

**[[8i24]] – AtSF-I6 + RNAP subunits α,β,β’,ω + DNA – ''Acetivibrio thermocellum'' - Cryo EM<br />

**[[8i23]] – AtSF-I1 + RNAP subunits α,β,β’,ω + DNA - Cryo EM<br />

**[[7ye1]] , [[7ye2]] – CcSF-70 + RNAP subunits α,β,β’,ω + DNA + GcrA – Cryo EM<br />

**[[7f0r]] – PaSF-38 in transcription activation complex + SutA – Cryo EM<br />

**[[7xl3]], [[7xl4]] – PaSF-S in transcription activation complex + SutA – Cryo EM<br />

**[[7xya]] – PaSF-70 in transcription antitermination complex + ALPA – Cryo EM<br />

**[[8gzg]], [[8gzh]] – SF-A + RNAP subunits α,β,β’,ω + DNA + RNA – ''Synechocystis'' - Cryo EM<br />

**[[8h40]] – AnSF-A + RNAP subunits α,β,β’,ω + DNA + NtcA – ''Anabaena'' - Cryo EM<br />

**[[8h3v]] – AnSF-A + RNAP subunits α,β,β’,ω + DNA + NtcA + NtcB - Cryo EM<br />

**[[7vpd]], [[7vpz]], [[7x74]], [[7x75]], [[7x76]] – ScSF-A + RNAP subunits α,β,β’,ω + metal uptake regulation protein + DNA + RNA - Cryo EM<br />

**[[68hkc]] – EcSF-32 in transcription initiation complex – Cryo EM<br />

**[[6pmi]], [[6pmj]] – EcSF-28 in transcription initiation complex – Cryo EM<br />

**[[5ipl]], [[5ipm]], [[5ipn]] – EcSF-38 in transcription initiation complex <br />

**[[8dy7]], [[8dy9]] – SvSF-A + RNAP subunits α,β,β’,ω + WhiA + WhiB + RbpA + DNA - Cryo EM<br />

**[[4oin]], [[4oip]], [[4oiq]], [[4oir]], [[5x21]] – TtSF-A in transcription initiation complex + antibiotic <br />

**[[6cuu]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + antibiotic<br />

**[[2a68]], [[2a69]], [[2a6h]], [[3dxj]], [[3eql]], [[4mq9]] – TtSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />

**[[5uhg]] – MtSF-A in transcription initiation complex + antibiotic + inhibitor<br />

**[[5uh6]], [[5uhc]], [[5uhd]], [[5uhb]] – MtSF-A in transcription initiation complex + antibiotic<br />

**[[6bzo]] – MtSF-A in transcription initiation complex + RbpA + antibiotic - Cryo EM<br />

**[[6vvt]], [[6vvx]], [[6vvz]] – MtSF-A in transcription initiation complex + antibiotic – Cryo EM<br />

**[[6vvy]], [[6vw0]] – MtSF-A in transcription open promoter complex + antibiotic – Cryo EM<br />

**[[6m7j]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA + antibiotic – Cryo EM<br />

**[[6eec]], [[6ee8]], [[6edt]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + CARD + DNA + antibiotic – Cryo EM<br />

**[[6ccv]] – MsSF-A in transcription initiation complex + peptide + RbpA + antibiotic<br />

**[[7l7b]] – SF-A + RNAP subunits α,β,β’,ω + antibiotic – Clostridia bacterium - Cryo EM<br />

**[[4mex]], [[4kmu]], [[4kn4]], [[4kn7]], [[4xsx]], [[4xsy]], [[4xsz]] [[4zh3]], [[4zh4]], [[5uac]], [[5uah]], [[5ual]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />

**[[7szj]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic – Cryo EM<br />