29on: Difference between revisions
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==Crystal structure of the staphylococcal efflux pump QacA in the inward open state in complex with nanobody 89== | |||
<StructureSection load='29on' size='340' side='right'caption='[[29on]], [[Resolution|resolution]] 3.32Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[29on]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=29ON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=29ON FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.32Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>, <scene name='pdbligand=OXM:OXAMIC+ACID'>OXM</scene>, <scene name='pdbligand=PGT:(1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+STEARATE'>PGT</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=29on FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=29on OCA], [https://pdbe.org/29on PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=29on RCSB], [https://www.ebi.ac.uk/pdbsum/29on PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=29on ProSAT]</span></td></tr> | ||
[[Category: Govaerts | </table> | ||
[[Category: Hutchin | == Function == | ||
[https://www.uniprot.org/uniprot/QACA_STAAU QACA_STAAU] Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Govaerts C]] | |||
[[Category: Hutchin A]] | |||
[[Category: Jodaitis L]] | |||
Latest revision as of 06:21, 22 April 2026
Crystal structure of the staphylococcal efflux pump QacA in the inward open state in complex with nanobody 89
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