12ru: Difference between revisions
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==In situ cryo-EM structure of axonal microtubules from ghost neurons (expanded lattice)== | |||
<StructureSection load='12ru' size='340' side='right'caption='[[12ru]], [[Resolution|resolution]] 3.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[12ru]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=12RU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=12RU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.66Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=12ru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=12ru OCA], [https://pdbe.org/12ru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=12ru RCSB], [https://www.ebi.ac.uk/pdbsum/12ru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=12ru ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBA1A_MOUSE TBA1A_MOUSE] Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (By similarity). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (By similarity). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (By similarity).[UniProtKB:P68363] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Biertumpfel C]] | |||
[[Category: Bodakuntla S]] | |||
[[Category: Marelli J]] | |||
[[Category: Mizuno N]] | |||
[[Category: Vasquez-Montes V]] | |||
Latest revision as of 16:41, 25 September 2026
In situ cryo-EM structure of axonal microtubules from ghost neurons (expanded lattice)
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