1yk8: Difference between revisions

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-[[Image:1yk8.gif|left|200px]]
+{{Seed}}
+[[Image:1yk8.png|left|200px]]
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 {{STRUCTURE_1yk8|  PDB=1yk8  |  SCENE=  }}
-'''Cathepsin K complexed with a cyanamide-based inhibitor'''
+===Cathepsin K complexed with a cyanamide-based inhibitor===
-==Overview==
+<!--
-Conversion of the proline-derived cyanamide lead to an acyclic cyanamide capable of forming an additional hydrogen bond with cathepsin K resulted in a large increase in inhibitory activity. An X-ray structure of a co-crystal of a cyanamide with cathepsin K confirmed the enzyme interaction. Furthermore, a representative acyclic cyanamide inhibitor 6r was able to attenuate bone resorption in the rat calvarial model.
+The line below this paragraph, {{ABSTRACT_PUBMED_15896958}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15896958 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15896958}}
 ==About this Structure==
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 [[Category: Cysteine]]
 [[Category: Protease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 16:25:30 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:05:19 2008''

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